Sumerians gave us our oldest written records, so Dragon Queen crown belongs to Tiamat. The makers of these D & D picked up on something quicker than I did – Tiamat is noteworthy. The Game of Thrones have a dragon queen, for a reason. The Japanese specialize in this area of mythology and own some cool stuff. The hero versus the dragon classifies as a universal myth; Tiamat versus Enki or Marduk may classify as the fist recorded myths.
I refer to Tiamat in the first chapter of novel, at present time. Chronologically she seemed a good fit. The Enki and Innana myth has played a part, in my story, for a long time. I added Tiamat in my last draft.
The Rise of Tiamat Tyranny of Dragons and Hoard of the Dragon Queen by Wizards RPG Team