Ancient Greece preferred their gods to take exceptional human form, so Ptolemy I created Seapis by merging Apis, the bull, with Osiris, the castrated. Isis already had a human appearance and her marriage to Osiris shifted to Serapis. Isis compares to the mother and daughter combo of Demeter and Persephone. Isis and Serapis had a large cult following in Rome. The destruction of the Temple of Serapis at Alexandria signifies the destruction of Paganism.