The Yamasee tribe has a complicated history but they definitely wiped out the Spanish speaking tribes of Florida, under the name of Seminoles they applied some finishing touches. What initially complicates Yamasee history is they were once a Spanish speaking tribe known as the Guale. A Spanish mission in Georgia served and tormented the Guale.
Native American tribes practiced polygamy and the Catholic Church didn’t allow two wives which led to many problems but one of the first of note happed when the Guale chief wasn’t allowed a second wife so he wiped out the friars serving at the mission. Eventually the Guale tribe was split in two and the anti-Spanish faction became the Yamasee. Apparently some Guale went to Florida and joined with the Spanish speaking tribes of Florida. Ties between the factions made from the Guale may have remained and both may have been called the Yamasee but one group was very anti-Spanish and history notes the attacks on the tribes of Florida, such as the Timucua and the Ais. Wikipedia says the Yamasee wiped out the Ais but it should be noted they and the Seminoles are the reason some of the Timucua went with the Spanish to Cuba. My Native American ancestor had a Spanish name, Seminoles have English derived names to go with their tribal name, for this reason my ancestor was likely Timucuan. Without a doubt the Seminoles got their Florida lands and their casino money from violence to the Spanish speaking tribes of Florida. I’m an ex-nuke from the US Navy, does anyone think I can’t avenge my Timucuan ancestors if I do choose, and the Seminoles are definitely part Yamasee.